Metkinen Chemistry - reagents for DNA and RNA synthesis Metkinen Chemistry - Reagents for RNA and DNA synthesis.
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6-(bis(4-methoxyphenyl)(4-(methylsulfinyl)phenyl)methylamino)hexyl 2-cyanoethyl diisopropylphosphoramidite

Catalogue number: 501-10

Purity: > 95%

Description: yellowish viscous oil

Storage of dry compound: 3 years at -20ºC

The DMS(O)MT-protection of aliphatic amino-group is easier to cleave compared to the MMT-function. The sulfoxy derivative can either be cleaved with standard deblock solution on the synthesizer, or left intact for HPLC “Trityl-on purification”. At the same time, the DMS(O)MT group is fully compatible with cartridge purification. The DMS(O)MT+ appears more stable than MMT+ and therefore does not reattach itself to an amine.

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